The Abit IX38 QuadGT uses the Intel LGA 775/ Socket T CPU socket. Any compatible Intel CPU will have the same socket entry. It uses the aging DDR2 memory type, with maximum speeds of up to 1066 MHz, and 0 DDR2 slots allowing for a maximum total of 8 GB RAM. DDR2 memory is exceptionally out of date, and considering how cheap DDR3 RAM is, using a motherboard with only DDR2 compatibility in a modern system build would be a very bad idea.

Conforming to the ATX standard, the Abit IX38 QuadGT should fit into the majority of cases. ATX is the most common form factor, and as such has a high degree of compatibility with other components while providing a decent number of slots to widen your expansion options.

The Abit IX38 QuadGT has 6 SATA 2.0 hard drive slots. These allow for data speeds of up to 3GB/s. SATA 2.0 is a very common standard, and despite the emergence of SATA 3.0 - whose potential is difficult to reach currently - SATA 2.0 remains a viable option.

The Abit IX38 QuadGT does not support onboard graphics. Any system build that uses this motherboard therefore requires a separate graphics card, or a processor that has a GPU on the same die, such as AMD APU processors. There are 2 PCIe x16 slots on this motherboard. This means it is perfectly capable of accommodating the latest graphics cards, although it is important to try and use a graphics card with the same graphics card interface of PCIe v2.x, as anything below will not reach the motherboard's potential, and anything above will have its performance slashed to the bandwidth maximum of the Abit IX38 QuadGT's PCIe v2.x. The Abit IX38 QuadGT supports up to 2 AMD Crossfire connected graphics cards for improved overall graphical performance at the cost of multiplied graphics-based power consumption as well as the price of the cards themselves. Nvidia SLI is not supported.

The Abit IX38 QuadGT has 8 USB 2.0 slots but no USB 3.0 slots. While USB 3.0 slots are so far by no means necessary, and with a plethora of USB 2.0 peripherals to choose from, the USB functionality on this motherboard should be fine. If planning on building a new system, a motherboard with USB 3.0 is likely to have a longer life cycle, however.